Methicillin-resistant Staphylococcus aureus bacteremia with elevated vancomycin minimum inhibitory concentrations.
Alexandra G MillsAmy C DupperKieran I ChackoBremy AlburquerqueDevika NadkarniAna Berbel CabanLindsey FoxMelissa Randy GitmanAjay OblaHarm van BakelDeena R AltmanPublished in: Antimicrobial stewardship & healthcare epidemiology : ASHE (2023)
This case-control study of 25 cases with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia with vancomycin minimum inhibitory concentration (MIC) ≥ 2 µg/mL and 391 controls (MIC < 2 µg/mL) characterized the clinical characteristics, treatments, and outcomes associated with elevated vancomycin MIC. Elevated vancomycin MIC was associated with baseline hemodialysis, prior MRSA colonization, and metastatic infection.
Keyphrases
- methicillin resistant staphylococcus aureus
- staphylococcus aureus
- squamous cell carcinoma
- small cell lung cancer
- gram negative
- peritoneal dialysis
- type diabetes
- end stage renal disease
- chronic kidney disease
- adipose tissue
- metabolic syndrome
- insulin resistance
- skeletal muscle
- weight loss
- multidrug resistant
- glycemic control