Correlation of ERG immunohistochemistry with molecular detection of TMPRSS2-ERG gene fusion.

Ji-Youn SungHwang Gyun JeonByong Chang JeongSeong Il SeoSeong Soo JeonHyun Moo LeeHan Yong ChoiSo Young KangYoon-La ChoiGhee Young Kwon

Published in: Journal of clinical pathology (2015)

ERG IHC is a useful surrogate test for the detection of TMPRSS2-ERG gene fusion, but it needs to be interpreted with caution and definite judgement should not be based on IHC alone. A relatively low incidence of TMPRSS2-ERG gene fusion was demonstrated in this Korean cohort.

Keyphrases

copy number
genome wide
genome wide identification
risk factors
gene expression
dna methylation
transcription factor
quantum dots