Self-Expanding or Balloon-Expandable TAVR in Patients with a Small Aortic Annulus.

Howard C HerrmannRoxana MehranDaniel J BlackmanStephen BaileyHelge MöllmannMohamed Abdel-WahabWalid Ben AliPaul D MahoneyHendrik RugeDavid A WoodSabine BleizifferBasel RamlawiHemal GadaAnna Sonia PetronioCharles D ResorWilliam MerhiBruno Garcia Del BlancoGuilherme F AttizzaniWayne B BatchelorLinda D GillamMayra GuerreroToby RogersJoshua D RovinMolly SzerlipBrian WhisenantG Michael DeebKendra J GrubbRatnasari PadangMyra T FanAndrew D AlthouseDidier Tchétchénull null

Published in: The New England journal of medicine (2024)

Among patients with severe aortic stenosis and a small aortic annulus who underwent TAVR, a self-expanding supraannular valve was noninferior to a balloon-expandable valve with respect to clinical outcomes and was superior with respect to bioprosthetic-valve dysfunction through 12 months. (Funded by Medtronic; SMART ClinicalTrials.gov number, NCT04722250.).

Keyphrases

aortic valve
aortic stenosis
transcatheter aortic valve replacement
aortic valve replacement
transcatheter aortic valve implantation
oxidative stress
early onset
ejection fraction
left ventricular
heart failure
pulmonary hypertension
pulmonary artery