Variant allele frequency in circulating tumor DNA correlated with tumor disease burden and predicted outcomes in patients with advanced breast cancer.
Jianxin ZhongHanfang JiangXiaoran LiuHao LiaoFeng XieBin ShaoShidong JiaHuiping LiPublished in: Breast cancer research and treatment (2024)
ctDNA VAF associated with tumor disease burden, and was a prognostic factor for patients with ABC. A combination of ctDNA test and radiographic imaging might enhance tumor burden evaluation, and improve prognosis stratification in patients with ABC.