The Association between Neprilysin gene polymorphisms and Alzheimer's disease in Tibetan population.

Siwei ChenDunzhu MimaHaiqiang JinQu DanFei WangJuan CaiLin ShiHua-Li WangAilian DuYing TangYongan Sun

Published in: Brain and behavior (2020)

NEP gene loci (rs701109, rs989692, rs9829757, rs3736187, rs1816558, rs6776185) were polymorphic in Tibetan population. No difference was found between these loci but for that male gender combined with allele C of NEP gene locus (rs701109) and T of gene locus (rs3736187) might be risk factors for AD in Tibet.

Keyphrases

genome wide
copy number
genome wide association study
dna methylation
transcription factor
genome wide identification