Antiviral kinetics of tenofovir alafenamide and tenofovir disoproxil fumarate over 24 weeks in women of childbearing potential with chronic HBV.
Calvin Qian PanTing-Tsung ChangSi Hyun BaeMaurizia BrunettoWai-Kay SetoCarla S CoffinSusanna K TanShuyuan MoJohn F FlahertyAnuj GaggarMindie H NguyenMustafa Kemal ÇelenAlexander ThompsonEdward J GanePublished in: PloS one (2021)
In WOCBP with high VL, no differences were found between TAF and TDF in reducing HBV DNA to levels associated with lower transmission risk. These data support ongoing studies of TAF for pMTCT.
Keyphrases
- hepatitis b virus
- liver failure
- antiretroviral therapy
- polycystic ovary syndrome
- circulating tumor
- electronic health record
- cell free
- breast cancer risk
- single molecule
- big data
- pregnancy outcomes
- case control
- type diabetes
- gestational age
- cervical cancer screening
- data analysis
- insulin resistance
- skeletal muscle
- drug induced
- artificial intelligence
- circulating tumor cells