Albuminuria: An Underappreciated Risk Factor for Cardiovascular Disease.
Joshua I BarzilayYoussef M K FaragJeffrey DurthalerPublished in: Journal of the American Heart Association (2024)
Albuminuria, an established biomarker of the progression of chronic kidney disease, is also recognized as a biomarker for the risk of cardiovascular disease. Elevated urinary albumin excretion indicates kidney damage and systemic vascular disease, including myocardial capillary disease and arterial stiffness. Albuminuria is associated with an increased risk of coronary artery disease, stroke, heart failure, arrhythmias, and microvascular disease. There are now several therapeutic agents that can lead to albuminuria lowering and a reduction in cardiovascular risk. However, screening for albuminuria is still low. Considering the importance of multidisciplinary management of patients with cardiovascular disease, it is crucial that health care professionals managing such patients are aware of the benefits of albuminuria surveillance and management.
Keyphrases
- cardiovascular disease
- end stage renal disease
- chronic kidney disease
- heart failure
- coronary artery disease
- healthcare
- peritoneal dialysis
- type diabetes
- left ventricular
- ejection fraction
- atrial fibrillation
- newly diagnosed
- blood pressure
- cardiovascular events
- cardiovascular risk factors
- oxidative stress
- metabolic syndrome
- prognostic factors
- acute coronary syndrome
- percutaneous coronary intervention
- quality improvement
- patient reported outcomes
- congenital heart disease
- drug induced
- blood brain barrier
- health information
- brain injury
- cardiac resynchronization therapy
- subarachnoid hemorrhage