Neuropeptide W facilitates chronic gastric ulcer healing by the regulation of cyclooxygenase and NF-κB signaling pathways.

Sevil Arabacı TamerKadriye Sezen MermerÖmer ErdoğanÖzge ÇevikFeriha ErcanCahit BağcıTessa Corrine Catherina Jaspers

Published in: Inflammopharmacology (2024)

In conclusion, NPW facilitated the healing of gastric injury in rats via the inhibition of pro-inflammatory cytokine production, oxidative stress and neutrophil infiltration as well as the downregulation of COX-2 protein and NF-κB gene expressions.

Keyphrases

signaling pathway
oxidative stress
pi k akt
induced apoptosis
epithelial mesenchymal transition
lps induced
nuclear factor
ischemia reperfusion injury
copy number
protein protein
diabetic rats
gene expression
nitric oxide synthase
nitric oxide
binding protein
heat stress
genome wide analysis