Association of ERAP2 polymorphisms in Colombian HLA-B27+ or HLA-B15+ patients with SpA and its relationship with clinical presentation: axial or peripheral predominance.
John LondoñoAna M SantosJuan C RuedaEnrique Calvo-ParamoRuben Burgos-VargasGilberto Vargas-AlarconNancy Martinez-RodriguezSofia Arias-CorrealGuisselle-Nathalia MuñozDiana PadillaFrancy CuervoViviana Reyes-MartinezSantiago Bernal-MacíasCatalina Villota-ErasoLuz M Avila-PortilloConsuelo RomeroJuan F MedinaPublished in: RMD open (2021)
An association was found between HLA-B15+ patients with SpA and haplotype TGT of ERAP2 SNPs. On the other hand, HLA-B27+ patients with SpA were associated with ERAP2 haplotypes TGC and CAT. These associations could be related to the clinical presentation of the disease, specifically with a peripheral or axial predominance, respectively.
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