Recovery of adrenal function after stopping mitotane in patients with adrenocortical carcinoma.
Barbara AltieriOtilia KimpelFelix MegerleMario DetomasIrina ChifuCarmina Teresa FussMarcus QuinklerMatthias KroissFassnacht MartinPublished in: European journal of endocrinology (2024)
Our study demonstrates that adrenal recovery occurs in most patients after stopping mitotane, particularly when followed-up in specialized centers, but not in all. Elimination time of mitotane after treatment discontinuation is very long, but individually quite variable.