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Recovery of adrenal function after stopping mitotane in patients with adrenocortical carcinoma.

Barbara AltieriOtilia KimpelFelix MegerleMario DetomasIrina ChifuCarmina Teresa FussMarcus QuinklerMatthias KroissFassnacht Martin
Published in: European journal of endocrinology (2024)
Our study demonstrates that adrenal recovery occurs in most patients after stopping mitotane, particularly when followed-up in specialized centers, but not in all. Elimination time of mitotane after treatment discontinuation is very long, but individually quite variable.
Keyphrases
  • end stage renal disease
  • ejection fraction
  • newly diagnosed
  • chronic kidney disease