The first endovascular rat glioma model for pre-clinical evaluation of intra-arterial therapeutics.

Jaims LimAmmad A BaigBrianna M DonnellyLee D ChavesSuyog U PolCarmon KoenigsknechtDonald PionessaBennett R LevyLiza GutierrezVincent M TutinoElad I LevyAdnan H Siddiqui

Published in: Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences (2023)

We present the first endovascular IA rat glioma model that allows selective catheterization of the intracranial vasculature and assessment of IA therapies for gliomas without need for access and sacrifice of proximal cerebrovasculature.

Keyphrases

clinical evaluation
oxidative stress
high grade
small molecule
ultrasound guided