Targeting cancer stem cells and signaling pathways by resveratrol and pterostilbene.
Lingling ZhangXiang WenMengmeng LiShiming LiHui ZhaoPublished in: BioFactors (Oxford, England) (2017)
In past decades, increasing evidence regarding cancer stem cells (CSCs) may account for carcinogenesis, tumor drug-resistant, and metastasis. CSCs are even considered as the root causes of tumor recurrence and metastases. Targeting CSCs may provide a new clue to cure cancer. Epidemiological and clinical studies have suggested that intake of dietary natural products may bring health benefits including lowering risk of cancer incidence. In this review, we have particularly focused on targeting signaling pathways of CSCs by natural resveratrol and its dimethylated derivative pterostilbene. © 2017 BioFactors, 44(1):61-68, 2018.
Keyphrases
- cancer stem cells
- drug resistant
- papillary thyroid
- signaling pathway
- cancer therapy
- multidrug resistant
- squamous cell
- acinetobacter baumannii
- healthcare
- public health
- mental health
- risk factors
- pi k akt
- lymph node metastasis
- drug delivery
- body mass index
- induced apoptosis
- health information
- social media
- oxidative stress
- weight loss