Nodal histiocytic sarcoma with prominent eosinophilic infiltration: expression of eotaxin-2 on tumor cells.

Rintaro Ohe Takanobu Kabasawa Aya Utsunomiya Yuka Urano Takumi KitaokaKazushi SuzukiNaing Ye AungIchiro KawamuraKatsushi TajimaTomoharu IshiyamaMitsunori Yamakawa

Published in: Diagnostic pathology (2021)

We revealed that eotaxins induced the selective migration of eosinophils into tissues in this case. These eosinophils may affect the tumor remodeling and tumor biology characteristics of HS, such as fibrosis and lymphatic vessel proliferation.

Keyphrases

lymph node
gene expression
high glucose
diabetic rats
single cell
neoadjuvant chemotherapy
binding protein
oxidative stress
radiation therapy
rectal cancer
stress induced
liver fibrosis
locally advanced