Arrhythmias including Atrial Fibrillation and Congenital Heart Disease in Kleefstra Syndrome: a possible epigenetic link.
Sunil K VasireddiTanja Zdolsek DrakslerArianne BoumanJoost KummelingMatthew T WheelerNicolette ChunSiddharth SrivastavaJacqueline HarrisPaul Graham FisherSanjiv M NarayanPaul J WangNitish BadhwarTjitske KleefstraMarco Valentin PerezPublished in: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology (2024)
In addition to a high prevalence of CHD, evolving data reveals early-onset atrial tachyarrhythmias in young KS patients, including AF, even in the absence of structural heart disease.
Keyphrases
- congenital heart disease
- early onset
- atrial fibrillation
- end stage renal disease
- late onset
- left atrial
- ejection fraction
- newly diagnosed
- catheter ablation
- chronic kidney disease
- gene expression
- oral anticoagulants
- peritoneal dialysis
- heart failure
- direct oral anticoagulants
- left atrial appendage
- electronic health record
- prognostic factors
- machine learning
- middle aged
- coronary artery disease