Protective effect of valproic acid on ischemia-reperfusion induced spinal cord injury in a rat model.

Oya Akpinar Oruc Mehmet Gazi Boyacı Şerife Ozdinc Sefa Çelik Esra Aslan

Published in: The journal of spinal cord medicine (2023)

Comparative analyses between prophylactic VPA administration and post-IR interventions revealed congruence in their anti-inflammatory and anti-apoptotic ramifications. VPA can reduce spinal cord IR injury in an aortic occlusion model of rats.

Keyphrases

spinal cord
spinal cord injury
anti inflammatory
neuropathic pain
cell death
high glucose
diabetic rats
aortic valve
physical activity
single cell
pulmonary artery
drug induced
oxidative stress