Gastric GDF15 levels are regulated by age, sex, and nutritional status in rodents and humans.
V Pena-LeonR Perez-LoisM VillalonC FolgueiraS Barja-FernándezE PridaJ BaltarF SantosJ FernøT García-CaballeroR NogueirasM QuiñonesO Al-MassadiLuisa Maria SeoanePublished in: Journal of endocrinological investigation (2023)
Our results provide clear evidence that gastric GDF15 is a critical contributor of circulating GDF15 levels and can explain some of the metabolic effects induced by GDF15.
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