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Multisite biologic tissue SARS-CoV-2 PCR testing in kidney transplantation from a COVID-positive donor.

Rongjia ZhangMichael KuehtA Scott LeaHeather L StevensonJoseph GosnellPing RenMarisa C NielsenAaron MillerMuhammad MujtabaJeffrey Fair
Published in: Journal of surgical case reports (2022)
With a high community transmission rate, SARS-CoV-2 has profoundly exacerbated the shortage of organs. Although the risk of donor-recipient transmission of SARS-CoV-2 is anecdotally low, an organ-specific infection analysis of procured organs from SARS-CoV-2 positive donors has yet to be established. Using a combination of clinically available and research-only polymerase chain reaction methods, organ preservation fluid and renal parenchymal tissues were tested for SARS-CoV-2 from the kidney of a SARS-CoV-2-positive donor prior to transplantation. The recipient has remained SARS-CoV-2 negative and clinically well, with excellent graft function 120 days post-transplantation.
Keyphrases
  • sars cov
  • respiratory syndrome coronavirus
  • kidney transplantation
  • rheumatoid arthritis
  • mental health
  • healthcare
  • gene expression
  • stem cells
  • cell therapy
  • real time pcr