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YAP represses intestinal inflammation through epigenetic silencing of JMJD3.

Hua ZhuJiali LuMingYue FuPing ChenYali YuMin ChenQiu ZhaoMin WuMei Ye
Published in: Clinical epigenetics (2024)
Our findings elucidate an epigenetic mechanism by which YAP inhibits the inflammatory response in colitis through epigenetic silencing of JMJD3 by recruiting EZH2.
Keyphrases
  • dna methylation
  • inflammatory response
  • gene expression
  • oxidative stress
  • long non coding rna
  • toll like receptor
  • long noncoding rna