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Clinical, microbiological and genomic characterization of Gram-negative bacteria with dual carbapenemases as identified by rapid molecular testing.

Ammara MushtaqBremy AlburquerqueMarilyn ChungShelcie FabreMitchell J SullivanMichael NowakEmilia M SordilloJose PolancoHarm van BakelMelissa Randy Gitman
Published in: JAC-antimicrobial resistance (2023)
Here we characterized a series of DCPOs from New York City. Foreign travel, prior hospitalization, antibiotic usage and comorbidities were common among DCPO cases. All carbapenemases were encoded on plasmids, which may facilitate horizontal transfer.
Keyphrases
  • klebsiella pneumoniae
  • escherichia coli
  • multidrug resistant
  • copy number
  • gene expression
  • loop mediated isothermal amplification
  • dna methylation
  • genome wide
  • electron transfer