Somatic Mutational Profile of High-Grade Serous Ovarian Carcinoma and Triple-Negative Breast Carcinoma in Young and Elderly Patients: Similarities and Divergences.
Pedro Adolpho de Menezes Pacheco SerioGláucia Fernanda de Lima PereiraMaria Lucia Hirata KatayamaRosimeire Aparecida RoelaSimone MaistroMaria Aparecida Azevedo Koike FolgueiraPublished in: Cells (2021)
Most HGSOC and TNBC from young and elderly patients present an affected TSG, mainly TP53, as well as mutational signature 3; however, a few tumors only present an affected oncogene or no affected cancer-causing genes.