Chimeric antigen receptor (CAR) T cell-based targeting of CD317 as a novel immunotherapeutic strategy against glioblastoma.

Lena HänschMatthias Peipp Maximilian MastallDanielle VillarsRenier MyburghManuela SilginerTobias WeissDorothee Gramatzki Flavio VasellaMarkus G ManzMichael Weller Patrick Roth

Published in: Neuro-oncology (2023)

These data reveal a promising role of CD317-CAR T cell therapy against glioblastoma, which warrants further evaluation to translate this immunotherapeutic strategy into clinical neuro-oncology.

Keyphrases

cell therapy
stem cells
mesenchymal stem cells
single cell
nk cells
palliative care
electronic health record
genome wide
cancer therapy
gene expression
bone marrow