Acrolein plays a culprit role in the pathogenesis of diabetic nephropathy in vitro and in vivo.
Zhen-Jie TongChin-Wei KuoPo-Cheng YenChih-Ching LinMing-Tsun TsaiShing-Hwa LuYi-Ping ChangWen-Sheng LiuHan-Hsing TsouHsiao-Wei ChengHsiang-Tsui WangPublished in: European journal of endocrinology (2022)
These results together suggest that acrolein plays a role in the pathogenesis of DN and could be a diagnostic marker and effective therapeutic target to ameliorate the development of DN.
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