Chromosomal microarray analysis on uncultured chorionic villus sampling can be complicated by confined placental mosaicism for aneuploidy and microdeletions.

Shen GuMadison JerneganIgnatia B Van den VeyverSandra PeacockJanice SmithAmy Breman

Published in: Prenatal diagnosis (2018)

Abnormal CMA results from CVS specimens should be interpreted with caution when mosaicism is evident or suspected. Furthermore, confirmatory testing on amniotic fluid, which contains cells derived from the fetus, is recommended in these cases.

Keyphrases

induced apoptosis
cell cycle arrest
pulmonary embolism
cell death
copy number
signaling pathway
umbilical cord
cell proliferation
dna methylation
pi k akt
ultrasound guided