Recent advancement in ultrasound-assisted novel technologies for the extraction of bioactive compounds from herbal plants: a review.

Herbal plants comprise potent bioactives, and they have a potential for the development of functional foods. Ultrasonication technology can be used to enhance the efficiency and quality of these bioactivities. The present review discussed the ultrasound-assisted novel extraction technologies (supercritical carbon dioxide (CO 2 ) and high pressurized liquid), including mechanistic understanding, influencing factors, extract process efficiency, and the recovery of bioactives with an industrial perspective. The strong observations of this study are the novel ultrasound-induced extraction process variables, such as ultrasound amplitude, sonication time, temperature, solid-solvent ratio, and pressure, are significantly influenced and must be optimized for maximum recovery of bioactives. The novel green technologies (ultrasound and assisted) could remarkably improve the extraction efficiency and enhance the quality of green extract. This review will support technological understanding about the impact on process parameters for the extraction of bioactives for the development of functional foods and nutraceuticals.