Characteristics of fecal metabolic profiles in patients with irritable bowel syndrome with predominant diarrhea investigated using 1 H-NMR coupled with multivariate statistical analysis.
Jae Soung LeeSeok-Young KimYoon Shik ChunYoung-Jin ChunSeung Yong ShinChang Hwan ChoiHyung-Kyoon ChoiPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2020)
The patients with IBS-D were clearly differentiated from the HC and HC-L by fecal metabolite analysis using 1 H-NMR spectroscopy, and five fecal metabolites characteristic of IBS-D were found. The findings of this study could be used to develop alternative and complementary diagnostic methods and as a source of fundamental information for developing novel therapies for IBS-D.