The clinical spectrum and incidence of anti-MOG-associated acquired demyelinating syndromes in children and adults.

Casper L de MolYym WongE D van PeltBha WokkeTam SiepmanR F NeuteboomD HamannR Q Hintzen

Published in: Multiple sclerosis (Houndmills, Basingstoke, England) (2019)

This nationwide study shows that the overall incidence of MOG-IgG-seropositive disorders is 0.16 per 100,000 people. The distribution over the clinical phenotypes differs between adults and children. Seropositivity can be maintained over years even without clinical activity, while seronegative patients generally had no relapses.

Keyphrases

young adults
end stage renal disease
risk factors
ejection fraction
newly diagnosed
peritoneal dialysis