Virological History Predicts Non-sustained Viral Suppression with Long-Acting Cabotegravir and Rilpivirine Therapy, independent of Pharmacokinetic Parameters.
Felix GutiérrezMarta Fernández-GonzálezChristian LedesmaMaría Losada-EcheberríaEnrique Barrajón-CatalánJavier García-AbellánDaria De StefanoLeandro LópezMelissa Bello-PerezSergio PadillaMar MasiáPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2024)
Non-sustained viral suppression in PWH transitioning from stable oral ART to CAB+RPV LA was linked to pre-existing factors before transition. Higher VL pre-ART and incomplete suppression on oral therapy increased the risk, independent of PK parameters.