EPS8 phosphorylation by Src modulates its oncogenic functions.

Linah A ShahoumiHesam KhodadadiHusam BensretiBabak BabanWilliam Andrew Yeudall

Published in: British journal of cancer (2020)

Phosphorylation of EPS8 at Y602 is crucial for signalling to the cell cycle and may provide insight to explain reduced efficacy of dasatinib treatment.

Keyphrases

cell cycle
cell proliferation
protein kinase
transcription factor
tyrosine kinase
replacement therapy