Holoprosencephaly: A case series from an area with high mining-related pollution.

Tony Kayembe-KitengeToni Kasole LubalaPaul Musa ObadiaPatrick Katoto ChimusaCyrille Katshiez NawejCélestin Banza Lubaba NkuluKoenraad DevriendtBenoit Nemery

Published in: Birth defects research (2019)

We hypothesize that these cases of holoprosencephaly were connected to mining-related pollution, possibly via epigenetic alterations induced by paternal occupational exposure to toxic metals.

Keyphrases

heavy metals
human health
health risk assessment
risk assessment
particulate matter
dna methylation
climate change
air pollution