Cerebrospinal fluid concentrations of posaconazole in paediatric leukaemia patients.

Katharina KörholzMalcolm HolterhusKathrin GordonCharlotte Müller-OhremCarsten MüllerAndreas H Groll

Published in: The Journal of antimicrobial chemotherapy (2024)

Trough concentrations of posaconazole in the CSF after systemic administration were low but detectable in all subjects. Concurrent serum concentrations were in the target range for prophylaxis and treatment in 100% and 90%, respectively.

Keyphrases

cerebrospinal fluid
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
emergency department
intensive care unit
prognostic factors