Momordica charantia silver nanoparticles modulate SOCS/JAK/STAT and P13K/Akt/PTEN signalling pathways in the kidney of streptozotocin-induced diabetic rats.

Olusola Olalekan ElekofehintiVictor Oluwatoyin OyedokunOpeyemi IwaloyeAkeem Olalekan LawalOluwamodupe Cecilia Ejelonu

Published in: Journal of diabetes and metabolic disorders (2021)

Observation drawn from this study suggests that M. charantia nanoparticles ameliorate DN through regulation of SOCS/JAK/STAT and PI3K/Akt/PTEN signalling pathways.

Keyphrases

diabetic rats
pi k akt
signaling pathway
silver nanoparticles
cell proliferation
oxidative stress
cell cycle arrest
type diabetes
cell death
metabolic syndrome
endothelial cells
skeletal muscle
insulin resistance
high glucose
high fat diet
stress induced