Prediction of lisinopril pediatric dose from the reference adult dose by employing a physiologically based pharmacokinetic model.

Memoona RashidMuhammad SarfrazMosab ArafatAmjad HussainNasir AbbasMuhammad Waqas SadiqMuhammad Fawad RasoolNadeem Irfan Bukhari

Published in: BMC pharmacology & toxicology (2020)

Thus, PBPK seems to have predictability potential for pediatric dose since it takes into consideration the physiological changes related to age and gender.

Keyphrases

risk assessment
human health
young adults
drug induced