Genetic biomarkers related to hemarthrosis, inflammation, and cartilage structure in pediatric patients with hemophilic arthropathy.
José de Jesús López-JiménezRicardo Ortega-CervantesHilda Luna-ZáizarAna Lilia Fletes-RayasClaudia-Patricia Beltrán-MirandaRogelio Troyo-SanrománJanet Soto-PadillaAlberto Tlacuilo-ParraAna-Rebeca Jaloma-CruzPublished in: Molecular genetics & genomic medicine (2019)
The distribution of risk genotypes for MTHFR and TNFα-308GA suggests their association with clinical parameters of hemophilic arthropathy. Cohort studies are essential to verify these associations.