Sub-acute Inhalation Exposure to Aluminum Oxide Nanoparticles and its Effects on Wistar Rats as Opposed to the Micro-sized Chemical Analog.
Marina ZemlyanovaNina ZaitsevaMark StepankovAnna IgnatovaPublished in: Pharmaceutical nanotechnology (2024)
Greater toxicity of Al2O3 NPs as opposed to MPs is evidenced by a wider range of organs where their bioaccumulation occurs, more apparent pathomorphological and pathological functional changes. Established peculiarities of toxic effects produced by the analyzed nanomaterial should be considered when developing hygienic recommendations aimed at preventing and mitigating adverse impacts of Al2O3 NPs on human health under inhalation exposure.
Keyphrases
- oxide nanoparticles
- human health
- risk assessment
- climate change
- liver failure
- respiratory failure
- heavy metals
- clinical practice
- diffusion weighted imaging
- aortic dissection
- oxidative stress
- magnetic resonance imaging
- hepatitis b virus
- magnetic resonance
- emergency department
- intensive care unit
- health risk assessment