Feline mammary carcinoma-derived extracellular vesicle promotes liver metastasis via sphingosine kinase-1-mediated premetastatic niche formation.

Yi-Chih ChangHao-Ping LiuHsiao-Li ChuangJiunn-Wang LiaoPei-Ling KaoHsun-Lung ChanTer-Hsin ChenYu-Chih Wang

Published in: Laboratory animal research (2023)

Taken together, our findings uncover a previously uncharacterized mechanism underlying liver-metastasis of FMC and provide new insights into prognosis and treatment of this feline malignancy.

Keyphrases

protein kinase
tyrosine kinase