Critical evaluation of the American Joint Commission on Cancer (AJCC) 8th edition staging system for patients with Hepatocellular Carcinoma (HCC): A Surveillance, Epidemiology, End Results (SEER) analysis.

Sivesh Kathir KamarajahTimothy L FrankelChristopher SonnendayClifford S ChoHari Nathan

Published in: Journal of surgical oncology (2017)

The AJCC 8th edition staging system for HCC performs similarly to the 7th edition. Future revisions should consider substratification of early HCC, specifically by distinguishing solitary tumors >2 cm from multifocal tumors ≤5 cm, and by considering the prognostic impact of vascular invasion in multifocal tumors ≤5 cm. Future studies should aim to validate these findings.

Keyphrases

lymph node
current status
pet ct
public health
papillary thyroid
risk factors
cell migration
squamous cell
data analysis