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Preclinical evaluation of the combination of AZD1775 and irinotecan against selected pediatric solid tumors: A Pediatric Preclinical Testing Consortium report.

E Anders KolbPeter J HoughtonRaushan T KurmashevaYael P MosseJohn M MarisStephen W EricksonYuelong GuoBeverly A TeicherMalcolm A SmithRichard Gorlick
Published in: Pediatric blood & cancer (2020)
AZD1775 potentiates the effects of irinotecan across most of the xenograft lines tested, with effect size appearing to vary across tumor panels.
Keyphrases
  • cell therapy
  • stem cells
  • bone marrow