The impact of CD4+CD28null T lymphocytes on atrial fibrillation: a potential pathophysiological pathway.
Andreas HammerAlexander NiessnerPatrick SulzgruberPublished in: Inflammation research : official journal of the European Histamine Research Society ... [et al.] (2021)
Considering the available data in the literature, it needs to be assumed that CD4+CD28null T lymphocytes are mainly involved in the development of AF and disease progression. Of utmost importance, it can be considered as the result of a T-cell-mediated auto-immune reaction among myocardial tissue. However, mechanisms which recruit CD4+CD28null cells in cardiac tissue remain unclear and need further investigation.
Keyphrases
- atrial fibrillation
- left ventricular
- induced apoptosis
- systematic review
- cell cycle arrest
- left atrial
- heart failure
- catheter ablation
- electronic health record
- left atrial appendage
- big data
- oxidative stress
- percutaneous coronary intervention
- coronary artery disease
- signaling pathway
- human health
- cell proliferation