A Δ9-Tetrahydrocannabinol Physiologically-Based Pharmacokinetic Model Development in Humans.
Janthima MethaneethornChomkanang PoomsaidornKanyamas NaosangParichart KaewworasutManupat LohitnavyPublished in: European journal of drug metabolism and pharmacokinetics (2021)
A PBPK model of THC in humans was developed. The model could describe THC concentration-time profiles in several dosing scenarios (i.e., IV bolus, IV infusion, oral administration and inhalation).
Keyphrases