Plasma biomarker profile and clinical correlations in adult patients with Tuberous Sclerosis Complex.

Biagio Orlando Alessandra Morano Valeria ManziniEmanuele Cerulli IrelliMaria S Borioni Caterina Veroni Enrico Michele Salamone Chiara D'Amelio Elisa Moliterni Sandra Giustini Gabriele Ruffolo Ivan Arisi Mara D'Onofrio Anna Teresa Giallonardo Paola PiscopoCarlo Di Bonaventura

Published in: Neurology (2023)

Our exploratory study documented a significant increase of GFAP plasma concentration in TSC adult patients, correlated with their neurological severity, supporting the central role of astrocytopathy in TSC pathophysiology.

Keyphrases

blood brain barrier
cerebral ischemia