The endogenous opioid system modulates defensive behavior evoked by Crotalus durissus terrificus: Panicolytic-like effect of intracollicular non-selective opioid receptors blockade.

Fabrício CalvoBruno Lobão-SoaresRenato Leonardo de FreitasTatiana Paschoalin-MaurinTayllon Dos Anjos-GarciaPriscila MedeirosJuliana Almeida da SilvaThelma Anderson LovickNorberto Cysne Coimbra

Published in: Journal of psychopharmacology (Oxford, England) (2018)

These findings suggest a panicolytic-like effect of endogenous opioid receptors antagonism in the inferior colliculus on innate (panic attack) and conditioned (anticipatory anxiety) fear in rats threatened by rattlesnakes.

Keyphrases

chronic pain
pain management
immune response
sleep quality