Cognitive and White Matter Microstructure Development in Congenital Hypothyroidism and Familial Thyroid Disorders.

Katia Perri Letizia De Mori Domenico Tortora Maria Grazia Calevo Anna Elsa Maria Allegri Flavia Napoli Giuseppa Patti Daniela Fava Marco Crocco Maurizio Schiavone Emilio Casalini Mariasavina Severino Andrea Rossi Natascia Di Iorgi Roberto Gastaldi Mohamad Maghnie

Published in: The Journal of clinical endocrinology and metabolism (2021)

These findings indicate that children with CH are at risk of neurocognitive impairment and white matter abnormalities despite timely and adequate treatment. The association between offspring cognitive vulnerability and maternal thyroid disorders requires careful consideration.

Keyphrases

white matter
multiple sclerosis
climate change
young adults
high fat diet
early onset
birth weight
type diabetes
room temperature
adipose tissue
metabolic syndrome
combination therapy
insulin resistance
weight loss
smoking cessation
weight gain