Metagenomic sequencing complements routine diagnostics in identifying viral pathogens in lung transplant recipients with unknown etiology of respiratory infection.

Dagmara W LewandowskaPeter W SchreiberMacé M SchuurmansBettina RueheOsvaldo ZagordiCornelia BayardMichael GreinerFabienne D GeissbergerRiccarda CapaulAndrea ZbindenJürg BöniChristian BendenNicolas J MuellerAlexandra TrkolaMichael Huber

Published in: PloS one (2017)

This study highlights the potential of metagenomic sequencing for virus diagnostics in cases with previously unknown etiology of infection and in complex diagnostic situations such as in immunocompromised hosts.

Keyphrases

single cell
antibiotic resistance genes
sars cov
gram negative
clinical practice
risk assessment
climate change
multidrug resistant
human health
wastewater treatment
respiratory failure
extracorporeal membrane oxygenation
high throughput sequencing