Inhibition of Insulin Degrading Enzyme to Control Diabetes Mellitus and its Applications on some Other Chronic Disease: a Critical Review.

Md Shofiul AzamMd WahiduzzamanMd Reyad-Ul-FerdousMd Nahidul IslamMukta Roy

Published in: Pharmaceutical research (2022)

In this review, we summarised the factors that modulate insulin reformation by IDE and interaction of IDE and some recent reports on IDE inhibitors against AD and T2D. We also highlighted the latest signs of progress of the function of IDE and challenges in advancing IDE- targetted therapies against T2D and AD.

Keyphrases

type diabetes
glycemic control
adipose tissue
insulin resistance
adverse drug
weight loss