Fisetin ameliorates oxidative glutamate testicular toxicity in rats via central and peripheral mechanisms involving SIRT1 activation.

Fatma H RizkNema A SolimanSuzan E Abo-ElnasrHeba A MahmoudMuhammad Tarek Abdel GhafarRasha A ElkholyOla A ELshoraReham A MariahShaimaa Samir Amin MashalAmira A El Saadany

Published in: Redox report : communications in free radical research (2022)

Fisetin ameliorates MSG-induced testicular toxicity via central and peripheral mechanisms making it a promising therapeutic target for male infertility.

Keyphrases

oxidative stress
germ cell
diabetic rats
mouse model
chemotherapy induced
high glucose
ischemia reperfusion injury
drug induced
oxide nanoparticles
polycystic ovary syndrome
skeletal muscle
metabolic syndrome
insulin resistance