Exendin-4 Exacerbates Burn-Induced Morbidity in Mice by Activation of the Sympathetic Nervous System.

Xiao-Jing JiJi-Wei HaoGuang-Lei LiNing DongXin-Qi WangMin ZhouQing-Hong Zhang Yong-Ming Yao

Published in: Mediators of inflammation (2019)

Exendin-4 suppresses T cell function and promotes organ inflammation through the activation of the sympathetic nervous system, while elicits Th2 switch via GLP-1R in burn injury.

Keyphrases

oxidative stress
diabetic rats
wound healing
signaling pathway
high fat diet induced
drug induced
type diabetes
wild type