Identification of potential antigenic peptides of Brucella through proteome and peptidome.
Meijuan PeiAo DongXueping MaShulei LiYan GuoMenglan LiZhenghui WangHengliang WangLi ZhuChao PanYufei WangPublished in: Veterinary medicine and science (2022)
The peptides we screened could bind to MHC molecules. After being stimulated with antigen T epitopes, Memory T cells can stimulate T cell activation and promote immune responses. Our results indicated that the peptides we identified may be good candidate targets for the design of subunit vaccines and these results pave the way for the study of safer vaccines against Brucella.