Involvement of Hdac3-mediated inhibition of microRNA cluster 17-92 in bronchopulmonary dysplasia development.
Di WangHui HongXiao-Xia LiJing LiZhi-Qun ZhangPublished in: Molecular medicine (Cambridge, Mass.) (2020)
Altogether, the present study revealed that Hdac3 activated the EZH1-p65-Pgf axis through inhibiting miR-17 in the miR-17-92 cluster, leading to accelerated abnormal pulmonary angiogenesis and alveolarization of BPD mice.