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Three cases of BRAF mutation negative Erdheim-Chester disease with a challenging distinction from IgG4-related disease.

David SpoerlRaphaël AndréAurélie BornandJörg D Seebach
Published in: Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology (2021)
A correct diagnosis of ECD may take several years and often requires revisiting previous hypotheses. Reassessment of histological slides and more modern complementary exams such as PET-CT or BRAF and MAPK-ERK mutation analysis can help to confirm the diagnosis of ECD and to select effective therapy.
Keyphrases
  • pet ct
  • signaling pathway
  • pi k akt
  • positron emission tomography
  • cell proliferation
  • metastatic colorectal cancer
  • oxidative stress
  • bone marrow
  • data analysis