Intravenous tirofiban following successful reperfusion in intracranial large artery atherosclerotic stroke: A secondary analysis of a randomized clinical trial.
Jiacheng HuangWeilin KongChang LiuJiaxing SongJie YangChengsong YueLinyu LiJinrong HuYan TianZhouzhou PengChangwei GuoDahong YangXiang LiuJian MiaoXiao ZhangFengli LiJeffrey L SaverWenjie ZiPublished in: Annals of clinical and translational neurology (2023)
Among patients with acute intracranial LAA stroke and successful reperfusion following endovascular thrombectomy, adjunct intravenous tirofiban was associated with a higher rate of independent functional outcome, without higher rates of sICH or mortality. Confirmatory randomized trials in these patients are desirable.
Keyphrases
- cerebral ischemia
- acute ischemic stroke
- end stage renal disease
- atrial fibrillation
- acute myocardial infarction
- ejection fraction
- high dose
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- type diabetes
- subarachnoid hemorrhage
- blood brain barrier
- patient reported outcomes
- left ventricular
- percutaneous coronary intervention